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Ambience Healthcare

Ambience Healthcare

AI operating system that automates clinical documentation for doctors and hospitals.

20
Open Roles
Founded
2020
Headquarters
San Francisco, CA
Employees
201-500
Latest Round
Series C
Est. Valuation
~$1,250M
Seed
Series A
Series B
Series C
Series D+

Investment Thesis

🚀 What They Do

Ambience Healthcare builds an AI operating system for healthcare, centered on ambient AI that listens to patient-clinician conversations and automatically generates clinical documentation, addressing clinician burnout.

The company has exclusive contracts with major health systems like Cleveland Clinic and reached ~$30M ARR. Crossed unicorn status with its $243M Series C at $1.25B valuation.

🔥 The Problem

Doctors spend more time typing notes into electronic health records than talking to patients, fueling burnout and driving clinicians out of medicine at record rates.

🛠️ The Fix

Ambience listens to doctor-patient conversations in real time and auto-generates complete clinical notes across 100+ specialties, integrated directly into Epic, Cerner, and other major EHRs.

⏰ Why Now

Large language models finally handle medical terminology and complex visit context accurately enough for clinical use, and health systems are desperate as physician burnout hits crisis levels.

✅ The Proof

Used by Cleveland Clinic, UCSF Health, and Houston Methodist; 97.7 KLAS satisfaction score; 76% reduction in documentation time; ~$64M revenue; valued at $1.25B.

👥 The Team

Mike Ng (President, ex-Morgan Stanley/Calera Capital, MIT Sloan MBA) and Nikhil Buduma (CEO & Chief Scientist, MIT CS, author of O'Reilly's Fundamentals of Deep Learning) co-founded Ambience in 2020.

Funding & Investors

$2B$1.5B$1B$500M$0
Founded
Series A
Jun 2023
Amount Raised: $30M
Series A
Jun 2023
Post-Money Valuation: $130M
Series A
$130M est. val
$30M raised
Series B
Feb 2024
Amount Raised: $70M
Series B
Feb 2024
Post-Money Valuation: $350M
Series B
$350M est. val
$70M raised
Series C
Jul 2025
Amount Raised: $243M
Series C
Jul 2025
Post-Money Valuation: $1.3B
Series C
$1.3B est. val
$243M raised
20202021202220232024202520262027
Amount raisedEst. post-money valuationFounded
Series C$243MJul 2025
Lead: Oak HC/FT · a16z, OpenAI, Kleiner Perkins, Optum Ventures
Series B$70MFeb 2024
Lead: Kleiner Perkins · OpenAI, a16z, Optum Ventures
Series A$30MJun 2023
Lead: Andreessen Horowitz · Optum Ventures

Headcount Growth

4003002001000
2
64
127
180
204
224
244*
20202021202220232024202520262027
*Forecast assumes all 20 open roles are filled

20 Open Roles

Account Manager
YesterdayCare Transformation0
Business Operations Lead
6mo agoOperations0
Engineering Manager, Product
2mo agoEngineering0
GRC Analyst
25d agoEngineering0
Head of National Strategic Accounts
4mo agoSales0
National Strategic Account Executive
6mo agoSales0
Physician AI Researcher
6mo agoClinical0
Product Lead, Inpatient
3mo agoProduct & Design0
Product Manager, Ambulatory Autonomous Coding
YesterdayProduct & Design0
Product Manager, Emergency Department Platform
YesterdayProduct & Design0